Jason,Your specs seem to be fine. I have never heard of this before so I am going to have to get some more information before I can try to diagnose anything. First, when you open a StrataFrame solution, one of the samples that comes with the framework, for example, do those solutions have the same problem?
Do you have a StrataFrame menu within the Visual Studio designer? Do you have real-time virus scanning software turned on? Have you verified that your database connection to the SQL Server where the StrataFrame database is located is correct (click the StrataFrame->Database Connection... menu within VS)? How many processes do you have running in memory?
Let's start with this information and we can go from there.