Yes, you can bind a business object to an ObjectDataSource object.  However, there are a few caveats that you'll discover when running... such as pagination doesn't work properly, I don't think.  We it have on the list to create a DataSource object that will work properly in ASP.NET, but it is not available, yet.

ASP.NET has a data source control called ObjectDataSource. It can be used as data source in ASP.NET DataView. Can I bind StrataFrame business object to ObjectDataSource's business object?