I have numerous DevExpress grids and tree list controls in my application which I am binding to BOs using BusinessBindingSource controls.  I have recently discovered that DevExpress does a very poor job of releasing memory and disposing of their own object properly.  I have a lot of memory leaks coming up in my app because of this.  Now, to the part where SF is involved...I have been running memory profilers which are showing that the grids, trees, etc are still linked to the BBS which is preventing them from being disposed of properly at garbage collection. 

My theory is that the BBS is somehow dynamically creating columns in the grid or tree at runtime, but not manually disposing of them when it's unloaded.  DevExpress basically expects you to dispose of everything, so I'm wondering if somehow the BBS is still linked to the DevExpress controls and preventing them from being released from memory correctly.  Is this a possibility?

I can open and close a test form I have created without filling the BO that is linked to the BBS, and it releases all memory correctly when the form is closed.  If I fill the BO when opening the form, it will not release all memory once closed.  Any ideas here?

That is what I was referring to when talking about the BaseBO.  All of your BOs should inherit from a BaseBO that inherits BusinessLayer.  This allows you to provide base level logic for this very type of thing without having to code it for each individual BO and at the risk of the Dispose being overwritten.