Well, the first thing is to determine what you are fighting. Most environments do not set their DPI above 96 DPI, however, if this is going to be common place for you, then you may need to address this in a base class situation. If you recall in training, we suggest that you create your base UI controls that at the very minimum inherit off of the SF classes (even if nothing is added to the logic) for situations just like this. If you haven't done this, it isn't that big of a deal as you can do a mass replace to change the textbox types on your forms.
If you see some early threads on the forum, we had one person who wanted to run their desktop in 120 DPI. This did throw off some of the SF dialogs. I know that there are some that probably still need to be changes, but we addressed all of this through the autoscaling settings versus on a control by control basis.