e.Parameters(0).Value = 1e.Parameters(1).Value = "Second Parm"
e.Parameters(0).Value = Me.txtPOID.Text
e.Parameters(0).Value = Cint(Me.txtPOID.Text)
Just FYI, I would not use CInt(). It is very slow and is an obselete method. You should do most of your type conversions like this:
CType(Control.Text, System.Integer)