Ok..

So, I am using the DevEx LayoutControl and kept right-clicking that to no avail.  But as soon as I right click a textbox inside it, I get the PanelManager link.  Thanks...haha.

It uses a standard designer and is easy to access if you will just right-click anywhere within the PanelManager (even on top of a textbox within the PanelManager) for example.  You can then select the page or the PanelManager itself to access the designer options from the property sheet or designer arrow.  You can refer to the docs for more information.  But it is as easy as it will ever be to get to

I love the idea of the Panel Manager!  It's really really useful on forms where you use a lot of panels on top of each other and don't want to continuously "send to back".  I have one suggestion, though.  Is it possible to make it available a little easier?  Right now I have to either happen to click in the right area or go over to my properties and select it out of the list, then I can click the arrow to open its menu.  It would be great if it could show up at the bottom or be accessed off the form somehow.  Just some easier access to the PanelManager in general would be great.